최근 주요업적

아이크로진은 사람을 포함한 생물종의 다양한 유전체 분석, 질환 및 웰니스 관련 유전자 발굴연구를 수행했습니다.

Possible Role of Single Stranded DNA Binding Protein 3 on Skin Hydration by Regulating Epidermal DifferentiationPossible Role of Single Stranded DNA Binding Protein 3 on Skin Hydration by Regulating Epidermal Differentiation

Choi MR, Shin JM, Shin YA, Chang YH, Chang MY, Lim CA, Sohn KC, Seo YJ, Kim CD, Lee JH, Lee Y.

Ann Dermatol. 2018 Aug;30(4):432-440. doi: 10.5021/ad.2018.30.4.432. Epub 2018 Jun 28.

Use of whole-exome sequencing to determine the genetic basis of signs of skin youthfulness in Korean women.

Chang YH, Shin YA, Kim JH, Kim HM, Lee DW, Chung HK, Kim SJ, Kim CD, Lee JH, Seo YJ, Im M, Lee Y.

J Eur Acad Dermatol Venereol. 2017 Mar;31(3):e138-e141. doi: 10.1111/jdv.13904. Epub 2016 Aug 30.

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB, Ferreira T, Chasman DI, … Shin YA, Sim X, Smit JH, …Hamsten A, Wichmann HE, Palmer CNA, Stefansson K, Ridker PM, Loos RJF, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB.

Nat Genet. 2016 Oct;48(10):1171-1184. doi: 10.1038/ng.3667. Epub 2016 Sep 12.

Identification of a possible susceptibility locus for UVB-induced skin tanning phenotype in Korean females using genome wide association study.

Kwak TJ, Chang YH, Shin YA, Shin JM, Kim JH, Lim SK, Lee SH, Lee MG, Yoon TJ, Kim CD, Lee JH, Koh JS, Seo YK, Chang MY, Lee Y.

Exp Dermatol. 2015 Dec;24(12):942-6. doi: 10.1111/exd.12809. Epub 2015 Sep 15.

Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan.

Ilyas M, Kim JS, Cooper J, Shin YA, Kim HM, Cho YS, Hwang S, Kim H, Moon J, Chung O, Jun J, Rastogi A, Song S, Ko J, Manica A, Rahman Z, Husnain T, Bhak J.

BMC Genomics. 2015 Mar 12;16:172. doi: 10.1186/s12864-015-1290-1. PMID: 25887915

Variation block-based genomics method for crop plants.

Kim YH, Park HM, Hwang TY, Lee SK, Choi MS, Jho S, Hwang S, Kim HM, Lee D, Kim BC, Hong CP, Cho YS, Kim H, Jeong KH, Seo MJ, Yun HT, Kim SL, Kwon YU, Kim WH, Chun HK, Lim SJ, Shin YA, Choi IY, Kim YS, Yoon HS, Lee SH, Lee S.

BMC Genomics. 2014 Jun 15;15:477. doi: 10.1186/1471-2164-15-477.

Minke whale genome and aquatic adaptation in cetaceans.

Yim HS, Cho YS, Guang X, Kang SG, Jeong JY, Cha SS, Oh HM, Lee JH, Yang EC, Kwon KK, Kim YJ, Kim TW, Kim W, Jeon JH, Kim SJ, Choi DH, Jho S, Kim HM, Ko J, Kim H, Shin YA, Jung HJ, Zheng Y, Wang Z, Chen Y, Chen M, Jiang A, Li E, Zhang S, Hou H, Kim TH, Yu L, Liu S, Ahn K, Cooper J, Park SG, Hong CP, Jin W, Kim HS, Park C, Lee K, Chun S, Morin PA, O'Brien SJ, Lee H, Kimura J, Moon DY, Manica A, Edwards J, Kim BC, Kim S, Wang J, Bhak J, Lee HS, Lee JH.

Nature Genetics 2014 Jan;46(1):88-92. doi: 10.1038/ng.2835. PMID: 24270359

The tiger genome and comparative analysis with lion and snow leopard genomes.

Cho YS, Hu L, Hou H, Lee H, Xu J, Kwon S, Oh S, Kim HM, Jho S, Kim S, Shin YA, Kim BC, Kim H, Kim CU, Luo SJ, Johnson WE, Koepfli KP, Schmidt-Küntzel A, Turner JA, Marker L, Harper C, Miller SM, Jacobs W, Bertola LD, Kim TH, Lee S, Zhou Q, Jung HJ, Xu X, Gadhvi P, Xu P, Xiong Y, Luo Y, Pan S, Gou C, Chu X, Zhang J, Liu S, He J, Chen Y, Yang L, Yang Y, He J, Liu S, Wang J, Kim CH, Kwak H, Kim JS, Hwang S, Ko J, Kim CB, Kim S, Bayarlkhagva D, Paek WK, Kim SJ, O'Brien SJ, Wang J, Bhak J.

Nat Commun. 2013;4:2433. doi: 10.1038/ncomms3433.

A genome-wide association study in Koreans identifies susceptibility loci for allergic nickel dermatitis.

Kim DS, Kim DH, Lee HM, Jee HJ, Lee Y, Chang MY, Kwak TJ, Kim CH, Shin YA, Lee JH, Yoon TJ, Lee MG.

Int Arch Allergy Immunol. 2013;162(2):184-6. doi: 10.1159/000353235. Epub 2013 Jul 31.

A genome-wide association study of a coronary artery disease risk variant.

Lee JY, Lee BS, Shin DJ, Woo Park K, Shin YA, Joong Kim K, Heo L, Young Lee J, Kyoung Kim Y, Jin Kim Y, Bum Hong C, Lee SH, Yoon D, Jung Ku H, Oh IY, Kim BJ, Lee J, Park SJ, Kim J, Kawk HK, Lee JE, Park HK, Lee JE, Nam HY, Park HY, Shin C, Yokota M, Asano H, Nakatochi M, Matsubara T, Kitajima H, Yamamoto K, Kim HL, Han BG, Cho MC, Jang Y, Kim HS, Euy Park J, Lee JY.

J Hum Genet. 2013 Mar;58(3):120-6. doi: 10.1038/jhg.2012.124. Epub 2013 Jan 31. PMID: 23364394.

Characterization of functional variants in 33 blood pressure loci using 1000 genomes project data

Lim, Ji Eun Shin, Young-Ah Hong, Kyung-Won Jin, Hyun-Seok et al.

Genes & genomics 2013 ISSN : 1976-9571

KAREBrowser: SNP database of Korea Association REsource Project.

Hong CB, Kim YJ, Moon SH, Shin YA, Cho YS, Lee JY.

BMB Rep. 2012 Jan;45(1):47-50.

BioSMACK: a linux live CD for genome-wide association analyses.

Hong CB, Kim YJ, Moon S, Shin YA, Go MJ, Kim DJ, Lee JY, Cho YS.

BMB Rep. 2012 Jan;45(1):44-6.

Clinical validation of colorectal cancer biomarkers identified from bioinformatics analysis of public expression data.

Jung YJ, Lee SH, Choi HS, Kim SN, Lee EY,Shin YA, Seo JH, Kim BJ, Jung YH, Kim WK, Chun HK, Lee WY, Kim JS.

Clin Cancer Res. 2011 Feb 15;17(4):700-9. doi: 10.1158/1078-0432.CCR-10-1300. Epub 2011 Feb 8.

Genome-wide Survey of Copy Number Variants Associated with Blood Pressure and Body Mass Index in a Korean Population.

Moon SH, Kim YJ, Kim YK, Kim DJ, Lee JY, Go MJ, Shin YA, Hong CB, Kim BJ

Genomics Inform. 2011 Dec;9(4):152-160

Clinical validity of the lung cancer biomarkers identified by bioinformatics analysis of public expression data.

Kim BJ, Lee HJ, Choi HY, Shin YA, Nam SY, Seo GJ, Son DS, Jo JS, Kim JS, Lee JS, Kim JO, Kim KM, Lee SH.

Cancer Res. 2007 Aug 1;67(15):7431-8.

ECgene: an alternative splicing database update.

Lee YS, Lee YH, Kim BJ, Shin YA, Nam SY, Kim PR, Kim NS, Chung WH, Kim JS, Lee SH.

Nucleic Acids Res. 2007 Jan;35(Database issue):D99-103. Epub 2006 Nov 28.

ECgene: genome annotation for alternative splicing.

Kim P, Kim N, Lee Y, Kim B, Shin YA, Lee S.

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D75-9. PMID: 15608289